Agenda 21 indicates that most of the data and methods for chemical risk assessment are generated in the developed countries and an expansion and acceleration of the assessment work will call for a considerable increase in research and safety testing by industry and research institutions. Agenda 21 cost projections address the need to strengthen capacities of relevant UN bodies and are based on current experience in IPCS. It should be noted that there are considerable costs, often not possible to quantify, that are not included. These comprise costs to industry and government of generating the safety data underlying the assessments and costs to governments of providing background documents and draft assessment statements to IPCS, the International Register of Potentially Toxic Chemicals (IRPTC) and OECD. They also include the cost of accelerated work in non-UN bodies such as OECD and EEC/EC.