Problem

Progressive muscular atrophy

Other Names:
Aran-Duchenne muscular atrophy
Adult spinal muscular atrophy
Nature:

Progressive muscular atrophy (PMA), also called Duchenne–Aran disease and Duchenne–Aran muscular atrophy, is a disorder characterised by the degeneration of lower motor neurons, resulting in generalised, progressive loss of muscle function.

PMA is classified among motor neuron diseases (MND) where it is thought to account for around 4% of all MND cases.

PMA affects only the lower motor neurons, in contrast to amyotrophic lateral sclerosis (ALS), the most common MND, which affects both the upper and lower motor neurons, or primary lateral sclerosis, another MND, which affects only the upper motor neurons. The distinction is important because PMA is associated with a better prognosis than ALS.

Related UN Sustainable Development Goals:
GOAL 3: Good Health and Well-being
Problem Type:
E: Emanations of other problems
Date of last update
04.10.2020 – 22:48 CEST