Problem

Spinal muscular atrophy


Experimental visualization of narrower problems
Nature:

Spinal muscular atrophy (SMA) is a term for a group of inherited neuromuscular diseases. All forms of the disease affect specialized nerve cells called lower motor neurons in the base of the brain and the spinal cord. These which control the movement of voluntary muscles, used for activities such as crawling, walking, head and neck control and swallowing. Most affected are the proximal muscles, or in other words the muscles closest to the point of origin, in this case those closest to the trunk of one's body. Weakness in the legs is generally greater than weakness in the arms.

Background:

There are several distinct form of this disease, with those of later onset of lesser severity. Infant forms cause early childhood death. Those with juvenile spinal muscular atrophy often require a wheelchair later in life but life span is usually not affected. Adult spinal muscular atrophy causes progressive and generalized weakness and muscle wasting with muscle twitches. The X-linked form affects men only. The senses/feelings are normal as is intellectual activity. In fact it is often observed that patients with SMA are unusually bright and sociable.

Incidence:

1 in 40 people are carriers of the gene for SMA; 1 in every 6,000 live births are affected.

Problem Type:
E: Emanations of other problems
Date of last update
13.05.2019 – 16:16 CEST