Problem

Letterer-Siwe disease

Nature:

Letterer–Siwe disease is one of the four recognized clinical syndromes of Langerhans cell histiocytosis (LCH). It causes approximately 10% of LCH disease and is the most severe form. Prevalence is estimated at 1:500,000 and the disease almost exclusively occurs in children less than three years old. The name is derived from the names of Erich Letterer and Sture Siwe.

Broader Problems:
Diseases of metabolism
Values:
Disease
Subject(s):
Medicine Pathology
Problem Type:
G: Very specific problems
Date of last update
05.05.1999 – 00:00 CEST