Problem
Opioid withdrawal
Nature:
Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden cessation or reduction of opioids where previous usage has been heavy and prolonged. Signs and symptoms of withdrawal can include drug craving, anxiety, restless legs syndrome, nausea, vomiting, diarrhea, sweating, and an elevated heart rate. Opioid use triggers a rapid adaptation in cellular signaling pathways that, when reduced or stopped, can cause adverse physiological effects. All opioids, both recreational drugs and medications, when reduced or stopped, can lead to opioid withdrawal symptoms. When withdrawal symptoms are due to recreational opioid use, the term opioid use disorder is used, whereas when due to prescribed medications, the term prescription opioid use disorder is used. Opioid withdrawal can be managed by the use of opioid replacement therapy, while symptoms may be relieved by the use of medications such as lofexidine and clonidine.
Broader Problems:
Abuse of opiatesWithdrawal from addictive substances Values:
Withdrawal Subject(s):
Societal Problems → Addiction, drug abuseHealth Care → Pharmacy
Problem Type:
G: Very specific problems Date of last update
01.01.2000 – 00:00 CET