Haemorrhagic fever with renal syndrome

Other Names:
HFRS Haemorrhagic nephroso-nephritis
Korean haemorrhagic fever
Russian (Yaroslav) haemorrhagic fever
Epidemic haemorrhagic fever

Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a group of clinically similar illnesses caused by species of hantaviruses. It is also known as Korean hemorrhagic fever and epidemic hemorrhagic fever. It is found in Europe, Asia, and Africa. The species that cause HFRS include Hantaan orthohantavirus, Dobrava-Belgrade orthohantavirus, Saaremaa virus, Seoul orthohantavirus, Puumala orthohantavirus and other orthohantaviruses. Of these species, Hantaan River virus and Dobrava-Belgrade virus cause the most severe form of the syndrome and have the highest morbidity rates. When caused by the Puumala virus, it is also called nephropathia epidemica. This infection is known as sorkfeber (vole fever) in Swedish, myyräkuume (mole fever) in Finnish, and musepest (mouse plague) in Norwegian.

Both HFRS and hantavirus pulmonary syndrome (HPS) are caused by hantaviruses, specifically when humans inhale aerosolized excrements of infected rodents. Both diseases appear to be immunopathologic, and inflammatory mediators are important in causing the clinical manifestations.

Broader Problems:
Haemorrhagic fevers
Narrower Problems:
Seoul virus
Related UN Sustainable Development Goals:
GOAL 3: Good Health and Well-being
Problem Type:
G: Very specific problems
Date of last update
04.10.2020 – 22:48 CEST