Squamous cell carcinoma


Squamous cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that result from squamous cells. These cells form the surface of the skin and lining of hollow organs in the body and line the respiratory and digestive tracts.

Common types include:

Squamous cell skin cancer: A type of skin cancer Squamous-cell carcinoma of the lung: A type of lung cancer Squamous cell thyroid carcinoma: A type of thyroid cancer Esophageal squamous cell carcinoma: A type of esophageal cancer Squamous-cell carcinoma of the vagina: A type of vaginal cancer

Despite sharing the name "squamous cell carcinoma", the SCCs of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment.

The risk of squamous cell carcinoma increases by 50% with smoking. In a 1996 US study of 107,000 nurses, squamous cell carcinoma occurred 50 percent more frequently in smokers than in those who had never smoked. Smoking interferes with the skin's ability to protect itself against damage by free radicals, highly reactive substances that are omnipresent in tobacco smoke.
Broader Problems:
Skin cancers
Lifestyle diseases
Narrower Problems:
Kaposi's sarcoma
Related Problems:
Problem Type:
G: Very specific problems
Biosciences Cytology
Medicine Cancer
Related UN Sustainable Development Goals:
GOAL 3: Good Health and Well-being
Date of last update
06.03.2001 – 00:00 CET