Urea, the principal organic solid in urine, is neither dangerous or poisonous, although like other substances in the body too much urea can be harmful. Not only is urea a source of nitrogen, but research has shown that urea aids in the synthesis and efficient use of protein. It has also been proven to be an extraordinary antibacterial and antiviral agent and is one of the best known natural diuretics. Urea was discovered and isolated as long ago as 1773 and is currently marketed in a variety of different drug forms, notably topical skin treatments. It also has great (almost entirely unused) potential as fertilizer.
The world's largest fertility drug-producing company, the Ares-Serono Group, produces the drug Pergonal by collecting urine samples from hundreds of thousands postmenopausal women volunteers in Italy, Spain, Brazil and Argentina. From 26 collection centres, the urine is sent to Rome where technicians then isolate the ovulation-enhancing hormone. Ares-Serono earned a reported $855 million in sales in 1992, and people pay up to $1,400 per month for this urine extract. A Dutch firm reported mixes the urine of nuns with that of pregnant women to make a potion for sterile couples.
Other examples of commercial medical applications of urine and urea in use today are: [Ureaphil]: a diuretic made from urea; [Urofollitropin]: a urine-extract fertility drug; [Ureacin]: urea cream for skin problems; [Amino-Cerv]: urea cream used for cervical treatments; [Premarin]: a urine-extract oestrogen supplement; [Panafil]: urea/papain ointment for skin ulcers, burns and infected wounds. Another urine-related product ingredient is carbamide, which is the chemical name for synthesised urea. Carbamide is used in products like ear drops and skin moisturisers.
2. In almost 100 years of laboratory and clinical studies on the use of natural urine and simple urea in medicine, extraordinary results have been obtained, but no toxic or dangerous side-effects to the user have ever been observed or reported by either researchers or patients using the therapy.