A wide variety of drugs have been used, either singly or in combination, including: digitalis (-in), to slow down the heart (a champion normally has a congenitally slow pulse rate); strychnine, ephedrin and caffeine, to delay the onset of fatigue; and anorexic drugs, to aid an athlete to lose weight so that he can get into a lower weight group. In most common use, however, are amphetamines and related drugs, which are taken as stimulants; or tranquillisers, which include barbiturates and meprobromate, to combat anxiety, particularly in shooting competitions. Even strong analgesic drugs such as morphine or dextromonoramide (palfium) may be used to reduce pain due to excessive effort, as in cycling, or due to injury, as in boxing. The ease with which chemical tests for doping can be made has tended considerably to restrict the use of these drugs, but in recent times they have been replaced by the corticoids (cortisone affects the cerebral nerve cells and also plays a role in resisting stress, thereby enabling competitors to maintain long periods of effort); and especially by the anabolic steroids, which by synthesizing the tissue substances, particularly proteins, promote the growth of muscle volume when taken during training. The latter substances are sometimes known as 'muscle fertiliser'.
Drugs used may be pain-killers which give rise to euphoria, and suppress the sensation of fatigue which is, physiologically, a danger sign. The athlete surpasses himself - which is the object he is aiming for - but he has made too great an effort and thereby suffers from acute overstrain. In other cases, in a cycle race for example, euphoria makes the athlete oblivious to danger, and reflex changes (or more serious mental disorders) may lead to serious accidents. Finally, amphetamines contribute to the development of hyperthermia which can result in heat-stroke, sudden collapse during a race, psychological disorders, heart failure and coma. The use of corticoids can lead to duodenal ulcers, oedema, intermittent or premature heartbeats, osteoporosis, and mental troubles. Continued heavy dosing with anabolic steroids can lead to aggressive character modifications, hypertension, hypertrophy of the prostate (with a risk of cancer), and alterations in the liver - in some cases even to adenomas or to cancer of the liver. Testosterone, which is a natural anabolic hormone, may lead to sterility. There is also a risk of virilism in the sportsman or arrest of growth in adolescents.
2. Since antiquity, man has always sought to improve his natural performance; however, it is the public's craze for sporting records together with the progress of pharmacology that have made doping a social evil during recent years. Secretly and widely used during sporting competitions, reputedly miraculous products are often sold at exorbitant prices by the trainers. It has been called the 'cancer of sport', and what is more important, young people are often tempted to follow the example set by the professionals.
3. The acceleration of doping has been the fruit of the years of cold war between East and West. But the real victims of the confrontation between East and West are the athletes of the Third World. They have to pit themselves against both professionals and those who dope.