Niemann-Pick type C disease
Nature: Although similar in name, Type C Niemann-Pick is very different from Types A and B at the biochemical and genetic level. Patients with Type C are not able to metabolize cholesterol and other lipids properly. Consequently, excessive amounts of cholesterol accumulate within the liver and spleen and excessive amounts of other lipids accumulate in the brain.
Incidence: Niemann-Pick Type C notably affects the Spanish-American population of southern New Mexico and Colorado.
Problem Type: G: Very specific problems
Date of last update 04.10.2020 – 22:48 CEST