Problem

Urea cycle disorders

Nature:

The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic.

The urea cycle converts highly toxic ammonia to urea for excretion. This cycle was the first metabolic cycle to be discovered (Hans Krebs and Kurt Henseleit, 1932), five years before the discovery of the TCA cycle. This cycle was described in more detail later on by Ratner and Cohen. The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.

Broader Problems:
Congenital metabolic diseases
Related UN Sustainable Development Goals:
GOAL 3: Good Health and Well-being
Problem Type:
E: Emanations of other problems
Date of last update
04.10.2020 – 22:48 CEST