Central core disease
Nature: First described in 1956, central core disease is a slowly progressive disease of voluntary muscle, or those necessary for movement. It is disabling but not life-threatening. It normally affects the hips and legs, although it can eventually involve most of the body's voluntary muscles.
Background: People who have central core disease are sometimes susceptible to malignant hyperthermia, a condition brought on by anaesthesia during surgery. Malignant hyperthermia causes a rapid, and occasionally fatal, rise in body temperature and produces muscle stiffness.
Problem Type: G: Very specific problems
Date of last update 13.09.1998 – 00:00 CEST