Problem

Simple goitre

Other Names:
Colloid goitre
Congenital hypothyroidism
Nature:
The causes for simple goitres are: (1) Enlargement of thyroid gland is common during puberty and 2) pregnancy due to increased physiological demand. Some drugs like thioureas, thiocyanates, iodine, para aminosalicylic acid, lithium can also cause goiter on long term administration. Dyshormonogenetic goiter is caused by defective genes which prevent or decrease the synthesis of thyroid hormones due to biochemical defects. The final common pathway to goiter formation in each of these situation is due to hypersecretion of TSH which stimulates thyroid gland growth.
Related Problems:
Cretinism
Aggravates:
Multinodal goitre
Problem Type:
E: Emanations of other problems
Date of last update
26.09.1998 – 00:00 CEST
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