Problem

Familial periodic paralysis

Other Names:
Hypokalemic periodic paralysis
Hyperkalemic periodic paralysis
Adynamia episodica hereditaria
Normokalemic periodic paralysis
Nature:
Periodic paralysis is a general term applied to three distinct, though possibly related, non-lethal disorders of voluntary muscle. The three types of periodic paralysis are hypokalemic, hyperkalemic and normokalemic. Hypokalemic, hyperkalemic and normokalemic periodic paralysis differ from one another in age of onset, precipitating factors, clinical characteristics and response to therapy. All three are characterized by intermittent attacks of weakness, during which affected muscles become slack, weak and unable to contract. However, between attacks, the affected muscles usually work normally.

Intervals between attacks vary from days to months and even years. Does periodic paralysis become worse with age? Periodic paralysis can cause progressive weakness, but the number of attacks and their severity tend to decrease with age and the attacks may disappear altogether, especially in women.

Broader Problems:
Diseases of metabolism
Hereditary neuromuscular disease
Subject(s):
Medicine → Locomotive, integumentary system
Society → Family
Problem Type:
G: Very specific problems
Date of last update
04.10.2020 – 22:48 CEST