Problem
Congenital abnormalities
Experimental visualization of narrower problems
Other Names:
Congenital physical disordersCongenital malformation
Congenital disorders
Congenital deformities
Congenital diseases
Inborn errors
Nature:
Congenital deformities and disorders are either:
- attributable to faulty genetic information which affects the development of the foetus and shows at birth or in early childhood; the malformation may be inherited (be familial) or arise spontaneously in the individual egg, sperm or embryo;
- or arising from inherited genetic information from other internal or external factors, such as hormonal disturbance, drugs, toxins and mutagens (collectively called teratogens) and physical injury.
Types of common congenital anomalies include atresia (a normal opening or tube in the body is closed or absent), stenosis (abnormal narrowing of a bodily canal or passageway), malpositioning, malformation, discolouration or absence of an organ. Cysts, and accessory or multiple organs occur. Organs may show congenital malfunction.
Broader Problems:
Human birth defectsGenetic defects and diseases Narrower Problems:
Atresia of earSotos syndromeOllier diseaseGenetic deafnessMaffucci syndromeEar ossicle fusionFraternal asymmetryFraternal asymmetryCongenital hydrocephalusCongenital heart defectsCornelia de Lange syndromeCongenital anomalies of eyeCongenital metabolic diseasesCongenital anomalies of spleenCongenital immune deficienciesCongenital limb reduction defectsCongenital anomalies of chromosomesCongenital anomalies of genital organsCongenital anomalies of nervous systemCongenital anomalies of alimentary tractCongenital anomalies of circulatory systemCongenital anomalies of respiratory systemCongenital anomalies of musculoskeletal systemCongenital syndromes affecting multiple systemsCongenital anomalies due to infectious diseases in animalsCongenital anomalies of urinary systemKlippel-Trenaunay syndrome Related Problems:
Juvenile alcoholism Aggravates:
DeafnessHypertensionInfant mortalityPerinatal mortalityAnimal abnormalitiesNatural human abortionSudden unexpected infant deathDecline in human genetic endowment Strategies:
Studying developmental biologyStudying congenital anomaliesCorrecting congenital disorders Organizations:
Association of Genetic Support Australasia References:
Ciba Foundation: Congenital Disorders of ErythropoiesisBrock, D J: Early Diagnosis of Fetal DefectsRockford, Doris E: Drug Effects on the Fetus: medical research subject analysis with bibliographyKalter, Harold: Issues and Reviews in TeratologyMizejewski, Gerald and Porter, Ian S: Alpha-Fetoprotein and Congenital DisordersMilunsky, Aubrey: Genetic Disorders and the Fetus: diagnosis, prevention and treatmentEriksson, A W, et al: Population Structure and Genetic Disorders: proceedings of the 7th Sigfred Juselius Web Page(s):
World Health Organization: Congenital Anomalies Subject(s):
Biosciences → GeneticsBiosciences → Growth
Medicine → Malformations
Medicine → Pathology
Related UN Sustainable Development Goals:
Problem Type:
D: Detailed problems Date of last update
11.03.2020 – 13:32 CET